Holding(s) in Company

22 Aug 2007 15:17

Synexus Clinical Research PLC22 August 2007 TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to whichvoting rights are attached (ii): SYNEXUS CLINICAL RESEARCH PLC 2. Reason for the notification (please state Yes/No): ( ) An acquisition or disposal of voting rights: (YES) An acquisition or disposal of financial instruments which may result in theacquisition of shares already issued to which voting rights are attached: ( ) An event changing the breakdown of voting rights: ( ) Other (please specify) : ( ) 3. Full name of person(s) subject to the notification obligation (iii): BREWIN DOLPHIN SECURITIES LIMITED 4. Full name of shareholder(s) (if different from 3.) (iv): 5. Date of the transaction (and date on which the threshold is crossed orreached if different) (v): 20 AUGUST 2007 6. Date on which issuer notified: 21 AUGUST 2007 7. Threshold(s) that is/are crossed or reached: 5% 8. Notified details: A: Voting rights attached to shares Class/type of shares if possible using Situation previous to the Triggeringthe ISIN CODE transaction (vi) Number of Number of voting Rights shares (viii) ORDINARY SHARES 1,203,541 1,203,541GB00B0L20P03 Resulting situation after the triggering transaction (vii) Class/type of shares if Number of Number of voting % of votingpossible using the ISIN CODE shares rights (ix) rights Direct Direct Indirect Direct Indirect (x) (xi) ORDINARY SHARES N/A N/A 1,096,076 N/A 4.7338%GB00B0L20P03 B: Financial Instruments Resulting situation after the triggering transaction (xii) Type of Expiration Exercise/ Number of voting rights that may % offinancial Date Conversion be acquired if the instrument is votinginstrument (xiii) Period/ Date exercised/ converted. rights (xiv) Total (A+B)Number of voting rights % of voting rights 1,096,076 4.7338% 9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable (xv): INDIRECT - BREWIN NOMINEES (CHANNEL ISLANDS) LIMITED - 38,770 - 0.1674% INDIRECT - BREWIN NOMINEES LIMITED - 50,769 - 0.2193% INDIRECT - GILTSPUR NOMINEES LIMITED - 929,803 - 4.0157% INDIRECT - FOUR YARDS NOMINEES LIMITED - 23,000 - 0.0994% INDIRECT - BREWIN NOMINEES LIMITED A/C CHARITY - 53,734 - 0.232% Proxy Voting: 10. Name of the proxy holder: ................. 11. Number of voting rights proxy holder will cease to hold: ................. 12. Date on which proxy holder will cease to hold voting rights: ................. 13. Additional information: FIGURES BASED ON SHARES IN ISSUE OF 23,154,172. THE INDIRECT VOTING RIGHTS UNDER (9) RELATE TO SHARES HELD IN CLIENT PORTFOLIOS,MANAGED BY THOSE FIRMS, UNDER DISCRETIONARY INVESTMENT MANAGEMENT AGREEMENTS. 14. Contact name: KATIE EDWARDS 15. Contact telephone number: 0191 279 7678 This information is provided by RNS The company news service from the London Stock Exchange