Oxford Biomedica Regulatory News (OXB)

For Immediate Release

27 May 2010

Name of applicant:

OXFORD BIOMEDICA PLC

Name of scheme:

Share Option Scheme

Period of return:

From:

28 November 2009

To:

27 May 2010

Balance of unallotted securities under scheme(s) from previous return:

4,036,539 Ordinary Shares of 1p each

Plus:  The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

None

Less:  Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

181,892 Ordinary Shares of 1p each

Equals:  Balance under scheme(s) not yet issued/allotted at end of period:

3,854,647 Ordinary Shares of 1p each

Name of contact:

Andrew Wood, Company Secretary

Telephone number of contact:

01865 783000