15 Dec 2015 07:00
15 December 2015
Motif Bio plc
("Motif" or the "Company")
Iclaprim Clinical Trial Supplies Manufactured
Motif Bio plc (AIM: MTFB), the clinical stage biopharmaceutical company specialising in developing novel antibiotics, today announced that clinical trial supplies in the form of sterile ampoules of iclaprim have been manufactured. Following Quality Assurance release, these supplies will be shipped to clinical trial sites. These activities enable Motif to remain on target to complete the two, previously announced Phase III ABSSSI trials in H2 2017.
Graham Lumsden, CEO, stated: "This is a major milestone for Motif given the complexity and costs usually associated with the manufacture of clinical trial supplies in sufficient quantity for large Phase III trials. We were able to utilise commercial-scale batches of the API (Active Pharmaceutical Ingredient) that we own as a result of our merger earlier this year with Nuprim Inc. This API, which we reprocessed to generate new material, has now been used to manufacture sterile ampoules for clinical trial supplies and we are on track to complete the trials in the second half 2017."
Enquiries:
Motif Bio plc Graham Lumsden (Chief Executive Officer) www.motifbio.com
| info@motifbio.com
|
Zeus Capital Limited (NOMINATED ADVISER and BROKER) Phil Walker/Dan Bate Dominic Wilson
| +44 (0) 20 3829 5000 |
Northland Capital Partners Limited (BROKER) Patrick Claridge/ David Hignell John Howes/ Mark Treharne (Broking) | +44 (0) 20 7382 1100 |
MC Services AG (TRADE PR) Raimund Gabriel Shaun Brown
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+49 (0) 89 210 2280 +44 (0) 207 148 5998 |
Plumtree Capital Limited (FINANCIAL ADVISOR) Stephen Austin
| +44 (0) 207 183 2493 |
Yellow Jersey PR Limited (FINANCIAL PR) Charles Goodwin Dominic Barretto
| +44 (0) 7747 788 221 |
Notes to Editors:
Motif is a clinical-stage biopharmaceutical company, specialising in the development of novel antibiotics that are designed to be effective against serious and life-threatening infections caused by multi-drug resistant bacteria. Our lead product candidate, iclaprim, is being developed for the treatment of the most common and serious bacterial infections such as acute bacterial skin and skin structure infections (ABSSSI) and hospital acquired bacterial pneumonia (HABP), including those caused by resistant strains such as MRSA (methicillin-resistant Staphylococcus aureus). Two Phase III ABSSSI clinical trials are on track to be completed in 2017 and if approved, iclaprim could be ready for commercialization in 2018. The Company is in discussions with pharmaceutical companies and universities to build a pipeline of innovative antibiotics targeting Gram-positive and Gram-negative bacteria. For additional information about Motif please visit www.motifbio.com.