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Pin to quick picksSyncona Share News (SYNC)

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Share Price: 108.80
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Syncona Invests GBP85 Million Into Freeline During Funding Round

Tue, 19th Jun 2018 08:32

LONDON (Alliance News) - FTSE 250-listed healthcare investment company Syncona Ltd said on Tuesday it has invested GBP85 million in Adeno-associated virus gene therapy company Freeline.

Adeno-associated virus is a small virus which infects humans and some other primate species.

The investment by Syncona is part of a GBP88.4 million Series B financing by Freeline, which is expected to allow Freeline to drive its lead programme in Haemophilia B through the clinic, enlarge its pipeline, improve on its core manufacturing capabilities and deliver its products to patients.

Syncona is one of two investors in Freeline, the other being UCL Technology Fund, which injected GBP3.4 million into the round. Syncona currently holds an 80% stake in the company, valued at GBP63.5 million during the first tranche of the investment.

"The business has a world leading founder and executive team with extensive track records in gene therapy, clinical translation, early and late stage development and global drug approvals. With its first programme now in the clinic we look forward to continuing to work with Freeline as it seeks to progress its treatments to patients," said Chief Investment Officer Chris Hollowood.

Shares in Syncona were up 0.5% at 224.00 pence on Tuesday.

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25 Jun 2024 12:56

IN BRIEF: Syncona Chair & CEO Hollowood buys GBP100,000 in shares

Syncona Ltd - London-based life science investor owns a diversified portfolio of companies spanning across clinical stages - Chair & Chief Executive Officer Chris Hollowood buys 89,588 shares at average price of GBP1.12, worth GBP99,980, in London on Monday.

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20 Jun 2024 12:11

Syncona adds two oncology investments to portfolio

(Sharecast News) - Life science investor Syncona announced the addition of two new oncology companies to its portfolio on Thursday.

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20 Jun 2024 10:22

Syncona swings to annual profit despite challenging market conditions

(Alliance News) - Syncona Ltd on Thursday offered up a resilient set of annual results, swinging to profit after a challenging year thanks in part to the strength of its life sciences portfolio.

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17 Jun 2024 13:15

Syncona to invest GBP40 million into newly created Spur Therapeutics

(Alliance News) - Syncona Ltd on Monday said it will provide further funding to a newly formed firm created after one of its portfolio companies acquired another.

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13 Jun 2024 16:05

UK earnings, trading statements calendar - next 7 days

Friday 14 June 
Tesco PLCTrading Statement
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Monks Investment Trust PLCFull Year Results
Tuesday 18 June 
Ashtead Group PLCFull Year Results
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Oxford BioDynamics PLCHalf Year Results
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Berkeley Group HoldingsFull Year Results
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Alpha Financial Markets Consulting PLCFull Year Results
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17 May 2024 14:34

Syncona notes Autolus's first quarter loss widens amid higher costs

(Alliance News) - Syncona Ltd on Friday noted that Autolus Therapeutics PLC reported an increased loss amid higher operating costs.

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9 May 2024 13:58

IN BRIEF: Syncona's Freeline gets positive results for Gaucher disease

Syncona Ltd on Thursday - London-based investor in healthcare companies - Says UK portfolio company Freeline Therapeutics Ltd presents positive new data from its phase I and II Galileo-1 study of FLT201, its novel gene therapy candidate, in Gaucher disease. Says FLT201 demonstrates a favourable safety and tolerability profile, with no infusion reactions and no severe adverse events. Syncona notes that Gaucher disease is a "debilitating genetic disorder caused by a deficiency of the GCase enzyme". Syncona Chief Executive Officer Chris Hollowood says: "We are very encouraged by the data generated from FLT201 which demonstrates a favourable safety and tolerability profile and significant enzyme activity. We are confident this treatment has the potential to challenge the standard of care in Gaucher disease, where current treatments are life-long and do not fully alleviate the disease." Freeline Therapeutics is based in Stevenage, Hertfordshire.

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9 May 2024 11:19

Syncona reports positive findings from investee Freeline

(Sharecast News) - Life science investor Syncona reported positive findings from its portfolio company Freeline Therapeutics on Thursday, after a phase one and two study of its gene therapy candidate for Gaucher disease, 'FLT20', showed encouraging results.

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3 May 2024 09:14

LONDON BROKER RATINGS: Jefferies cuts AJ Bell; Deutsche likes ConvaTec

(Alliance News) - The following London-listed shares received analyst recommendations Friday morning and Thursday:

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11 Apr 2024 14:22

Syncona agrees to sell stake in investee company for GBP7.4 million

(Alliance News) - Syncona Ltd on Thursday said it has reached an agreement to sell one of its portfolio companies to US biotechnology firm, Century Therapeutics Inc.

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4 Apr 2024 17:06

IN BRIEF: Syncona notes investee Achilles's annual loss narrows

Syncona Ltd - London-based investor in healthcare companies - Notes that the loss of investee and clinical-stage biopharmaceutical company Achilles Therapeutics PLC narrows by 2.7% to USD68.2 million in 2023 from USD71.1 million in 2022. General and administrative costs contract by 19% to USD17.0 million from USD21.1 million. According to Syncona's website, the company has a 25% stake in Achilles.

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14 Mar 2024 14:16

Syncona portfolio company Autolus posts widened loss for 2023

(Alliance News) - Syncona Ltd on Thursday noted the 2023 results of one of its life science portfolio companies, which showed a widened loss and an increase in annual expenses.

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12 Feb 2024 18:01

IN BRIEF: Freeline shareholders approve Syncona acquisition

Syncona Ltd - London-based investor in healthcare companies - Freeline Therapeutics Holdings PLC shareholders approve acquisition by Syncona.

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8 Feb 2024 13:45

UPDATE: Syncona portfolio strengthens thanks to Autolus

(Alliance News) - Syncona Ltd on Thursday said its portfolio company Autolus Therapeutics PLC has struck a deal to work with BioNTech to commercialise its CAR-T programmes.

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8 Feb 2024 09:41

Syncona portfolio strengthens in third quarter thanks to Autolus

(Alliance News) - Syncona Ltd on Thursday reported a recent increase to the value of its portfolio, as the company said it was in a strong position to push forward its main life science companies.

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