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Silence Therapeutics makes 'exceptional' year-to-date progress

Tue, 23rd Jun 2020 10:14

(Sharecast News) - RNA therapeutics developer Silence Therapeutics said on Tuesday that it had continued to make "exceptional progress" in securing additional high-value partnerships and advancing its proprietary pipeline year-to-date.
Silence stated preparations to submit an investigational new drug package for its prioritised and wholly-owned asset SLN360 to the US Food and Drug Administration were on schedule for later in 2020, while its SLN124 treatment was said to have already received Rare Paediatric Disease Designation for beta-thalassaemia and Orphan Drug Designation for myelodysplastic syndrome from the FDA.

In terms of liquidity, the AIM-listed group said it was in a strong position and had cash, cash equivalents and short-term deposits of £52m, reflecting proceeds from the issuance of ordinary shares to AstraZeneca in March and a $20m upfront payment from AstraZeneca in May.

Chairman Iain Ross said: "We continue to monitor the evolving Covid-19 pandemic but are pleased to note that we have not experienced any significant disruption to our operations.

"Our significantly strengthened balance sheet ensures that we are in a robust position to weather any uncertainty whilst equipping us with the capital to further accelerate our important RNAi programmes and platform."

As of 1015 BST, Silence shares were up 5.61% at 449.90p.
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26 Feb 2021 09:06

Silence to get $2m milestone payment from Mallinckrodt

(Sharecast News) - Silence Therapeutics announced on Friday that it would receive a $2m (£1.43m) milestone payment following the start of work on a third target being explored under its ongoing RNAi research collaboration with Mallinckrodt, for the treatment of complement pathway-mediated diseases.

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17 Feb 2021 11:57

IN BRIEF: Silence Therapeutics Begins Dosing In SLN360 Phase 1 Trial

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17 Feb 2021 08:12

Silence Therapeutics begins dosing in lipoprotein treatment trial

(Sharecast News) - Silence Therapeutics has started dosing subjects in the 'APOLLO' phase 1 clinical study of its wholly-owned lead product candidate 'SLN360', it announced on Wednesday, for the treatment of elevated lipoprotein-a (Lp(a)) levels.

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5 Feb 2021 09:34

Silence Therapeutics Raises USD45 Million In Private Share Placing

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5 Feb 2021 09:04

Silence Therapeutics raises ?33m to support pipeline development

(Sharecast News) - Novel therapeutics developer Silence Therapeutics announced an oversubscribed private placement of 2,022,218 American depositary shares (ADSs) on Friday, raising £33m to support the development of its pipeline.

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6 Jan 2021 14:27

UK EXECUTIVE CHANGE SUMMARY: Martin Gilbert Joins River & Mercantile

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6 Jan 2021 08:06

Silence Therapeutics taps Craig Tooman for CFO

(Sharecast News) - Drug discovery outfit Silence Therapeutics has named Craig Tooman as its new chief financial officer.

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12 Oct 2020 22:10

UK DIRECTOR DEALINGS SUMMARY: Tesco's Simon Patterson Buys Shares

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12 Oct 2020 11:13

e-Therapeutics Names New Chief Executive; Plans To Ramp Up Research

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8 Oct 2020 21:16

UK EXECUTIVE CHANGE SUMMARY: Silence Wants US CFO After Nasdaq Float

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14 Sep 2020 14:07

Silence Therapeutics Appoints Mark Rothera As CEO; Annual Loss Widens

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14 Sep 2020 13:14

Mark Rothera joins Silence Therapeutics as new CEO

(Sharecast News) - Drug discovery and development company Silence Therapeutics announced the appointment of Mark Rothera as its president and chief executive officer and board member on Monday, effective immediately.

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8 Sep 2020 19:23

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