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Industry groups back drugmakers' appeal in Zantac cancer lawsuits

Thu, 20th Jun 2024 16:01

June 20 (Reuters) - A bid by GSK and other drugmakers to stop more than 70,000 lawsuits in Delaware over discontinued heartburn drug Zantac has received the backing of leading U.S. industry groups, including the United States Chamber of Commerce and Pharmaceutical Research and Manufacturers of America.

In a friend-of-the-court brief posted to the Delaware Superior Court's docket on Thursday, the groups said that a Delaware judge's recent ruling allowing the lawsuits to proceed jeopardized the state's business-friendly reputation and threatened to turn it into "a hotbed of products-liability and mass-tort litigation."

GSK, Pfizer, Sanofi and Boehringer Ingelheim, which all sold Zantac at times, had asked Judge Vivian Medinilla to bar plaintiffs from offering expert testimony linking Zantac to cancer, arguing that it was not based on sound scientific methods. The plaintiffs' cases depend on that testimony, and cannot go to trial without it.

After the judge refused, the companies petitioned her for leave to appeal directly to the Delaware Supreme Court. The industry groups in Thursday's filing are asking the judge to grant that petition.

The groups, which also include the National Association of Manufacturers and the Biotechnology Innovation Organization, said Medinilla's ruling was at odds with a Florida federal court that in 2022 tossed about 50,000 Zantac claims after rejecting similar evidence as unreliable. Some plaintiffs are appealing that ruling.

If Delaware courts adopted a more relaxed evidence standard for mass tort cases, they said, the state would quickly become a venue of choice for plaintiffs since many U.S. companies are incorporated there.

The groups urged Medinilla to "consider the importance to the business community of clarity, consistency and predictability in Delaware jurisprudence on expert testimony."

A lawyer for the plaintiffs did not immediately respond to a request for comment.

First approved in 1983, Zantac became the world's best-selling medicine in 1988 and one of the first to top $1 billion in annual sales. It was originally marketed by a forerunner of GSK and later sold successively to other companies.

Lawsuits began piling up after the U.S. Food and Drug Administration in 2020 asked manufacturers to pull the drug off the market over concerns that its active ingredient, ranitidine, could degrade into a cancer-causing chemical called NDMA over time or when exposed to heat.

The drugmakers have maintained there is no evidence Zantac exposes users to harmful NDMA levels or causes cancer.

The vast majority of pending cases are in Delaware. Only one case, against GSK and Boehringer Ingelheim in Illinois, has gone to trial, ending in a victory for the companies last month. (Reporting By Brendan Pierson in New York, Editing by Alexia Garamfalvi and Rod Nickel)

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11 Jun 2024 00:32

GSK asks to appeal Delaware ruling allowing Zantac cases to go forward

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10 Jun 2024 22:49

Latest trial over Zantac cancer claims called off as plaintiff drops case

June 10 (Reuters) - A woman who claimed in a lawsuit that GSK's discontinued heartburn drug Zantac caused her breast cancer dropped her case shortly before it was set to go to trial in Illinois state court on Monday, the company announced.

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7 Jun 2024 19:34

What to know about bird flu in dairy cows and the risk to humans

CHICAGO, June 7 (Reuters) - The outbreak of bird flu in U.S. dairy cows has now been confirmed in Minnesota and Iowa, bringing to 11 the total number of affected states, which have been encouraged to ramp up testing efforts at the request of government officials.

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1 Jun 2024 21:35

Delaware judge lets more than 70,000 Zantac lawsuits go forward

June 1 (Reuters) - A Delaware judge has allowed more than 70,000 lawsuits over discontinued heartburn drug Zantac to go forward, ruling that expert witnesses can testify in court that the drug may cause cancer.

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1 Jun 2024 21:07

Delaware judge lets more than 70,000 Zantac lawsuits go forward

June 1 (Reuters) - A Delaware judge has allowed more than 70,000 lawsuits over discontinued heartburn drug Zantac to go forward, ruling that expert witnesses can testify in court that the drug may cause cancer.

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30 May 2024 20:56

What to know about bird flu in dairy cows and the risk to humans

CHICAGO, May 30 (Reuters) - A third U.S. dairy worker tested positive for bird flu after exposure to infected cows, and was the first to suffer respiratory symptoms, U.S. officials said on Thursday in the latest expansion of the outbreak. Bird flu has been found in dairy cattle in nine states. This second case in a Michigan dairy worker was found through increased testing of people and cows in the state following the April 1 identification of a case in a Texas farm worker. Here's what you need to know about the outbreak.

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27 May 2024 06:00

US, European nations consider vaccinating workers exposed to bird flu

CHICAGO/LONDON, May 27 (Reuters) - The United States and Europe are taking steps to acquire or manufacture H5N1 bird flu vaccines that could be used to protect at-risk poultry and dairy workers, veterinarians and lab technicians, government officials said, moves influenza experts say could curb the threat of a pandemic.

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23 May 2024 19:21

Zantac not a cause of woman’s cancer, jury says in first trial over drug

CHICAGO, May 23 (Reuters) - A jury in Chicago on Thursday rejected an Illinois woman’s claim that the now discontinued heartburn drug Zantac caused her colon cancer, in the first trial out of thousands of lawsuits making similar allegations.

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2 May 2024 19:57

GSK knew about Zantac cancer risk, attorneys tell jury in first trial

May 2 (Reuters) - U.S. attorneys for a woman who claims her colon cancer was caused by the now discontinued heartburn drug Zantac on Thursday told a jury in Chicago that pharmaceutical companies GSK and Boehringer Ingelheim knew the product could cause cancer if it was not handled properly but failed to warn the public.

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30 Apr 2024 23:46

First trial over Zantac cancer claims set to begin in Chicago

April 30 (Reuters) - The first trial over claims that blockbuster heartburn drug Zantac, once sold by GSK and other companies, causes cancer is set to begin this week in Chicago.

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30 Apr 2024 22:39

First trial over Zantac cancer claims set to begin in Chicago

April 30 (Reuters) - The first trial over claims that blockbuster heartburn drug Zantac, once sold by GSK and other companies, causes cancer is set to begin this week in Chicago.

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25 Apr 2024 07:52

Sanofi profit slips on generic competition and currency effects

April 25 (Reuters) - Sanofi's first-quarter operating income fell 14.7% as currency effects and cheap competition to its multiple sclerosis drug Aubagio outweighed rising sales of anti-inflammatory drug Dupixent, the French drugmaker said on Thursday.

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